Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.71 |
| ▸ | HPGD | P15428 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.69 |
| ▸ | NQO2 | P16083 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.58 |
| ▸ | TUBB | P07437 | 3/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958468 | 0.90 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL29628777 | 0.90 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL29198788 | 0.86 | KDM4E (0.66) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL29628842 | 0.86 | KDM4E (0.76) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL27566660 | 0.84 | NQO2 (0.72) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL6353272 | 0.84 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL9189433 | 0.84 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDMAPTTUBB4A | |
| SCHEMBL7511884 | 0.84 | DRD2 (0.61) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL3954004 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL3993248 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394905-B1 | Excitatory amino acid antagonists | MERRELL DOW PHARMA (US) | 1995-08-16 | — | — | EP | claimed |
| EP-0394905-B1 | Excitatory amino acid antagonists | MERRELL DOW PHARMA (US) | 1995-08-16 | — | — | EP | disclosed |