Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902452 | 0.90 | SLC16A3 (0.49) | PTGER4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11316855 | 0.82 | PTGER4 (0.71) | PTGER4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10507278 | 0.80 | PLA2G2A (0.44) | PTGER4ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL12077014 | 0.80 | PTGER4 (0.54) | PTGER4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13865229 | 0.77 | CNR1 (0.54) | PTGER4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27546370 | 0.76 | SLC16A3 (0.51) | PTGER4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9186085 | 0.76 | CNR1 (0.58) | PTGER4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14288003 | 0.75 | PTGER4 (0.53) | PTGER4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3426834 | 0.74 | PDE5A (0.52) | PTGER4ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10871571 | 0.74 | NPSR1 (0.47) | ALDH1A1CYP1A2CYP2D6CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382276-B1 | Ethers of 1-benzyl-3-hydroxymethyl-indazole with aliphatic 2-hydroxyacids | ACRAF (IT) | 1995-08-30 | — | — | EP | disclosed |