SCHEMBL9186282

SCHEMBL9186282

CC(=O)Oc1ccc(CSc2nnnn2-c2ccccc2NS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.47
LMNA P02545 2/20 0.47
MAPK1 P28482 4/20 0.45
TSHR P16473 3/20 0.45
ALOX15 P16050 1/20 0.45
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 2/20 0.42
PKM P14618 1/20 0.42
ATM Q13315 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
EP300 Q09472 1/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9186272 0.83 ALDH1A1 (0.52) ALDH1A1LMNAMAPK1TSHRL3MBTL1
SCHEMBL11875780 0.80 ALDH1A1 (0.72) ALDH1A1LMNAMAPK1TSHRHTT
SCHEMBL9183045 0.71 ALDH1A1 (0.56) ALDH1A1LMNAMAPK1TSHRHTT
SCHEMBL11878906 0.65 ALDH1A1 (0.64) ALDH1A1LMNAMAPK1TSHRSMN1; SMN2
SCHEMBL27889025 0.64 CA12 (0.65) ALDH1A1LMNAMAPK1HTTSMN1; SMN2
SCHEMBL8971065 0.64 TBXA2R (0.68) ALDH1A1LMNAHTTSMN1; SMN2MAPT
SCHEMBL24019811 0.63 HPGD (0.76) ALDH1A1LMNAMAPK1TSHRHTT
SCHEMBL10672858 0.63 MAPK1 (0.57) ALDH1A1LMNAMAPK1ALOX15HTT
SCHEMBL3290045 0.62 PTGDR2 (0.53) ALDH1A1MAPK1MAPTMEN1KMT2A
SCHEMBL25665594 0.62 PPARG (0.57) ALDH1A1LMNATSHRHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450198-B1 Developer liquid for high contrast development AGFA GEVAERT NV (BE) 1995-07-26 EP disclosed
US-5141843-A Phenyl tetrazole anti-fogging agent AGFA-GEVAERT N. V. (BE) 1992-08-25 US disclosed
EP-0450198-A1 Developer liquid for high contrast development AGFA-GEVAERT N.V. (BE) 1991-10-09 EP disclosed