Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.68 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SGMS1 | Q86VZ5 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11108981 | 0.88 | ALDH1A1 (0.59) | TBXA2RTBXAS1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8840166 | 0.87 | TBXA2R (0.64) | TBXA2RTBXAS1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10460747 | 0.82 | ALDH1A1 (0.63) | TBXA2RTBXAS1ALDH1A1MAPTMEN1 | |
| SCHEMBL11336056 | 0.82 | TBXA2R (0.65) | TBXA2RTBXAS1ALDH1A1POLBSMN1; SMN2 | |
| Sulotroban SCHEMBL34187 | 0.81 | TBXA2R (1.00) | TBXA2RTBXAS1ALDH1A1POLBMAPT | |
| SCHEMBL10462122 | 0.81 | TBXA2R (0.58) | TBXA2RTBXAS1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL12676129 | 0.81 | TBXA2R (0.71) | TBXA2RTBXAS1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL11332922 | 0.79 | TBXA2R (0.81) | TBXA2RTBXAS1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9127040 | 0.79 | TBXA2R (0.81) | TBXA2RTBXAS1ALDH1A1POLBMAPT | |
| SCHEMBL412302 | 0.79 | ALDH1A1 (0.79) | TBXA2RTBXAS1ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545671-A | ADMINISTERING A CYCLODEXTRIN CLATHRATE OF EPTALOPROST OR CICAPROST | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | disclosed |
| EP-0589037-B1 | INDIAN DERIVATIVE AND THROMBOXANE ANTAGONIST CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-05-29 | — | — | EP | disclosed |
| US-5409956-A | A sulfonylaminoalkylindan carboxylic acid or ester for treating thrombosis, vasospasm or asthma | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0589037-A1 | INDIAN DERIVATIVE AND THROMBOXANE ANTAGONIST CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-30 | — | — | EP | disclosed |
| WO-1991004739-A1 | USE OF PROSTACYCLIN DERIVATIVES AGAINST METASTASES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-04-18 | — | — | WO | disclosed |
| EP-0421562-A2 | Use of prostacyclin analogs against metastases | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-04-10 | — | — | EP | disclosed |