Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9179871 | 0.84 | ALDH1A1 (0.53) | MAPK1HSD17B10ALDH1A1GAAKMT2A | |
| SCHEMBL2872850 | 0.80 | TSHR (0.50) | PKMMAPK1HSD17B10ALDH1A1GAA | |
| SCHEMBL7228617 | 0.75 | ALDH1A1 (0.43) | MAPK1HSD17B10ALDH1A1GAAKMT2A | |
| SCHEMBL204946 | 0.73 | TSHR (0.67) | PKMMAPK1HSD17B10ALDH1A1GAA | |
| SCHEMBL29754649 | 0.73 | TSHR (0.67) | PKMMAPK1HSD17B10ALDH1A1GAA | |
| SCHEMBL529030 | 0.73 | HTT (0.41) | MAPK1ALDH1A1KMT2ATDP1HTT | |
| SCHEMBL20695629 | 0.72 | ALDH1A1 (0.56) | PKMMAPK1HSD17B10ALDH1A1GAA | |
| SCHEMBL8566976 | 0.71 | ATR (0.34) | HSD17B10ALDH1A1GAAKMT2AKDM4E | |
| Formic Acid SCHEMBL22719985 | 0.70 | MAPK1 (0.65) | PKMMAPK1HSD17B10ALDH1A1GAA | |
| SCHEMBL529031 | 0.70 | ALDH1A1 (0.56) | HSD17B10ALDH1A1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4634687-A | COCATALYST FOR COORDINATION CATALYST | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1987-01-06 | — | — | US | claimed |
| EP-0425701-B1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION | TONEN CORP (JP) | 1995-09-13 | — | — | EP | disclosed |
| EP-0425702-B1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION | TONEN CORP (JP) | 1995-09-13 | — | — | EP | disclosed |
| US-5177043-A | α-olefin polymerization catalyst component | TONEN CHEMICAL CORPORATION (JP) | 1993-01-05 | — | — | US | disclosed |
| US-5132261-A | Magnesium containing coordination catalyst, durability, storage stability | TONEN CORPORATION (JP) | 1992-07-21 | — | — | US | disclosed |
| US-5130283-A | Of metal oxide suppor type with high catalytic acitivity | TONEN CORPORATION (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0227455-B1 | PROCESS FOR PRODUCING CATALYST INGREDIENT FOR USE IN OLEFIN POLYMERIZATION | Tonen Corporation (JP) | 1991-08-28 | — | — | EP | disclosed |
| EP-0439622-A1 | CATALYTIC COMPONENT FOR ALPHA-OLEFIN POLYMERIZATION | Tonen Corporation (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0425701-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION | Tonen Corporation (JP) | 1991-05-08 | — | — | EP | disclosed |
| EP-0425702-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION | Tonen Corporation (JP) | 1991-05-08 | — | — | EP | disclosed |
| US-4727049-A | COORDINATION CATALYST CONTAINING OXIDE, DIHYDROCARBYL MAGNESIUM, HALOGEN CONTAINING ALCOHOL, ELECTRON DONOR AND TITANIUM COMPOUND | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1988-02-23 | — | — | US | disclosed |
| US-4716206-A | COCATALYST SYSTEM | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1987-12-29 | — | — | US | disclosed |
| EP-0227455-A2 | Process for producing catalyst ingredient for use in olefin polymerization | Tonen Corporation (JP) | 1987-07-01 | — | — | EP | disclosed |
| US-4647550-A | Catalyst component for polymerization of olefins | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1987-03-03 | — | — | US | disclosed |
| US-4634687-A | COCATALYST FOR COORDINATION CATALYST | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1987-01-06 | — | — | US | disclosed |
| US-4613579-A | MAGNESIUM, TITANIUM, HALO-ALCOHOL | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1986-09-23 | — | — | US | disclosed |
| EP-0173472-A2 | Catalyst component for polymerization of olefins | Tonen Corporation (JP) | 1986-03-05 | — | — | EP | disclosed |
| EP-0173470-A2 | Catalyst component for polymerization of olefins | Tonen Corporation (JP) | 1986-03-05 | — | — | EP | disclosed |
| EP-0171200-A2 | Catalyst component for polymerization of olefins | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1986-02-12 | — | — | EP | disclosed |
| EP-0136163-A2 | Process for polymerization of olefins | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1985-04-03 | — | — | EP | disclosed |