Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9187790 | 0.94 | HDAC8 (0.67) | HDAC8MMP1AKR1C3NPC1ERCC5 | |
| SCHEMBL25363727 | 0.87 | MMP1 (0.76) | MMP1ALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL27109591 | 0.85 | HDAC8 (0.55) | HDAC8MMP1AKR1C3NPC1ERCC5 | |
| SCHEMBL8782975 | 0.84 | HDAC8 (0.69) | HDAC8MMP1AKR1C3NPC1ERCC5 | |
| SCHEMBL7293621 | 0.82 | KDM4E (0.59) | MMP1GPR139SMN1; SMN2KDM4E | |
| SCHEMBL7515133 | 0.82 | KDM4E (0.59) | MMP1GPR139SMN1; SMN2KDM4E | |
| SCHEMBL27145544 | 0.82 | HPGD (0.54) | HDAC8MMP1AKR1C3NPC1GPR139 | |
| SCHEMBL1222467 | 0.81 | MMP1 (0.74) | MMP1ERCC5FEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27144604 | 0.80 | HPGD (0.49) | HDAC8MMP1AKR1C3NPC1GPR139 | |
| SCHEMBL20898454 | 0.80 | HPGD (0.55) | HDAC8NPC1GPR139ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375439-B1 | Geminal diphenyl derivatives and their use in immunoassays | SYNTEX INC (US) | 1995-09-06 | — | — | EP | disclosed |
| US-5378636-A | M-phenoxybenzoylaminoethanesulfonic acid to inactivate interfering binding proteins in immunoassay | SYNTEX (U.S.A.) INC. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5256575-A | For inactivating interfering binding proteins | SYNTEX (U.S.A.) INC. (US) | 1993-10-26 | — | — | US | disclosed |
| US-5063165-A | GEMINAL DIPHENYL DERIVATIVES AND THEIR USE IN IMMUNOASSAYS | SYNTEX (U.S.A.) INC. (US) | 1991-11-05 | — | — | US | disclosed |
| EP-0375439-A2 | Geminal diphenyl derivatives and their use in immunoassays | SYNTEX (U.S.A.) INC. (US) | 1990-06-27 | — | — | EP | disclosed |