Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2433951 | 0.93 | MAPT (0.58) | MAPTRAB9ANPC1GFERSMN1; SMN2 | |
| SCHEMBL9189119 | 0.86 | KDM1A (0.61) | MAPTRAB9ANPC1GFERSMN1; SMN2 | |
| SCHEMBL11618318 | 0.83 | RAB9A (0.85) | MAPTRAB9ANPC1GFERSMN1; SMN2 | |
| SCHEMBL6524056 | 0.82 | MAPT (0.69) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL1937499 | 0.79 | RAB9A (0.69) | MAPTRAB9ANPC1GFERSMN1; SMN2 | |
| SCHEMBL31613986 | 0.79 | RAB9A (0.69) | MAPTRAB9ANPC1GFERSMN1; SMN2 | |
| SCHEMBL9186989 | 0.79 | MEN1 (0.84) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL9187037 | 0.78 | KDM1A (0.53) | MAPTMEN1KMT2AKDM1APTPN1 | |
| SCHEMBL4381356 | 0.76 | RAB9A (1.00) | MAPTRAB9ANPC1GFERSMN1; SMN2 | |
| SCHEMBL11424504 | 0.75 | ALDH1A1 (0.52) | MAPTRAB9ANPC1GFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5176854-A | Xanthone Derivatives | HITACHI, LTD. (JP) | 1993-01-05 | — | — | US | claimed |
| EP-0315140-B1 | Non-linear optical device | HITACHI LTD (JP) | 1995-08-23 | — | — | EP | disclosed |
| US-5176854-A | Xanthone Derivatives | HITACHI, LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0315140-A2 | Non-linear optical device | HITACHI, LTD. (JP) | 1989-05-10 | — | — | EP | disclosed |