SCHEMBL9187635

SCHEMBL9187635

O=C(O)c1cc(OCc2ccc(CS(=O)(=O)c3ccccc3)cc2)ccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.58
LMNA P02545 1/20 0.55
MAOB P27338 3/20 0.49
MAOA P21397 2/20 0.49
SPHK1 Q9NYA1 5/20 0.46
SPHK2 Q9NRA0 4/20 0.46
PTGES O14684 1/20 0.46
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA4 P22748 2/20 0.45
CA5A P35218 2/20 0.45
CA7 P43166 2/20 0.45
CA5B Q9Y2D0 2/20 0.45
TSHR P16473 1/20 0.45
HSD17B10 Q99714 1/20 0.45
HNF4A P41235 1/20 0.45
CA9 Q16790 1/20 0.44
CTSV O60911 1/20 0.44
CTSL P07711 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9189807 0.91 MAOB (0.56) MCL1LMNAMAOBMAOASPHK1
SCHEMBL9186820 0.91 MCL1 (0.56) MCL1LMNAMAOBMAOASPHK1
SCHEMBL9191503 0.90 LMNA (0.52) MCL1LMNAMAOBMAOASPHK1
SCHEMBL343794 0.84 MCL1 (0.78) MCL1LMNAMAOBMAOAPTGES
SCHEMBL9187227 0.82 MCL1 (0.61) MCL1LMNAMAOBMAOAPTGES
SCHEMBL9190244 0.82 LMNA (0.49) MCL1LMNAMAOBMAOA
SCHEMBL9187030 0.82 MAOB (0.54) MCL1LMNAMAOBMAOASPHK1
SCHEMBL9189967 0.82 MCL1 (0.49) MCL1HSD17B10HNF4AMEN1KMT2A
SCHEMBL9185590 0.81 MCL1 (0.60) MCL1MAOBPTGESCA12CA1
SCHEMBL9303625 0.81 LMNA (0.53) MCL1LMNAMAOBMAOASPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0403833-B1 Recording material NEW OJI PAPER CO LTD (JP) 1995-09-27 EP disclosed
US-5276001-A Color developer comprising salicylic acid derivative KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-01-04 US disclosed
US-5094999-A Salicylic acid derivative KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1992-03-10 US disclosed
EP-0403833-A2 Recording material NEW OJI PAPER CO., LTD. (JP) 1990-12-27 EP disclosed