SCHEMBL9188014

SCHEMBL9188014

CC(O)Nc1nc(Cl)nc(Cl)n1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.60
TDP1 Q9NUW8 1/20 0.60
NFKB1 P19838 2/20 0.42
ALDH1A1 P00352 2/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
POLB P06746 1/20 0.37
CYP2C19 P33261 2/20 0.35
CYP2C9 P11712 1/20 0.35
NPR3 P17342 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CYP1A2 P05177 1/20 0.33
PDE4A P27815 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10078277 0.87 GAA (0.52) GAATDP1NFKB1ALDH1A1LMNA
SCHEMBL3297569 0.82 GAA (0.46) GAATDP1ALDH1A1LMNACYP1A2
SCHEMBL1923400 0.80 GAA (0.90) GAATDP1NFKB1ALDH1A1ALOX15
SCHEMBL9357101 0.76 GAA (0.48) GAATDP1NFKB1ALDH1A1ALOX15
Propazine SCHEMBL67521 0.75 GAA (1.00) GAATDP1ALDH1A1LMNASMN1; SMN2
Propazine SCHEMBL8539531 0.75 GAA (1.00) GAATDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL10410780 0.73 GAA (0.56) GAATDP1NFKB1ALDH1A1ALOX15
SCHEMBL17564550 0.73 GAA (0.56) GAATDP1NFKB1ALDH1A1ALOX15
SCHEMBL11044268 0.73 GAA (0.56) GAATDP1NFKB1ALDH1A1ALOX15
SCHEMBL9297026 0.73 GAA (0.50) GAATDP1NFKB1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0395074-B1 Method for producing a silver halide photographic photosensitive material MITSUBISHI PAPER MILLS LTD (JP) 1995-11-02 EP disclosed
EP-0356014-B1 Reactive Dyes ZENECA LTD (GB) 1994-11-30 EP disclosed
EP-0279122-B1 REACTIVE DYES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-06-10 EP disclosed
US-5102780-A 2,3-dichloro-1,3,5-triazine salt hardener in silver halide emulsion layer and/or gelatin layer on a polyethylene terephthalate support film; dimensional stability, stain resistance MITSUBISHI PAPER MILLS LIMITED (JP) 1992-04-07 US disclosed
US-5019134-A Triphenodioxazines IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-05-28 US disclosed
EP-0395074-A1 Method for producing a silver halide photographic photosensitive material MITSUBISHI PAPER MILLS, LTD. (JP) 1990-10-31 EP disclosed
US-4939243-A Water-soluble copper complex disazo compounds containg a chloro triazinylamino group and a group of the vinylsulfone series as fiber-reactive groups and their dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-03 US disclosed
EP-0356014-A1 Reactive Dyes ZENECA LIMITED (GB) 1990-02-28 EP disclosed
EP-0289023-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1988-11-02 EP disclosed