Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NPR3 | P17342 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295987 | 0.84 | KMT2A (0.39) | GAATDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11044268 | 0.77 | GAA (0.56) | GAATDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL28390117 | 0.76 | IDH1 (0.58) | — | |
| SCHEMBL22158831 | 0.76 | TDP1 (0.45) | GAATDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL22158830 | 0.76 | TDP1 (0.45) | GAATDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9188014 | 0.76 | GAA (0.60) | GAATDP1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8201839 | 0.75 | LMNA (0.31) | LMNA | |
| SCHEMBL6700072 | 0.75 | HTR7 (0.33) | GAATDP1ALDH1A1KMT2AKDM4E | |
| Methoxymethane SCHEMBL27642128 | 0.71 | NPC1 (0.31) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1923400 | 0.70 | GAA (0.90) | GAATDP1LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356014-B1 | Reactive Dyes | ZENECA LTD (GB) | 1994-11-30 | — | — | EP | disclosed |
| EP-0279122-B1 | REACTIVE DYES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-10 | — | — | EP | disclosed |
| US-5019134-A | Triphenodioxazines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |
| EP-0356014-A1 | Reactive Dyes | ZENECA LIMITED (GB) | 1990-02-28 | — | — | EP | disclosed |