Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922073 | 0.79 | NPSR1 (0.72) | NPSR1NFKB1BRD4KAT2BBRD9 | |
| SCHEMBL24123895 | 0.79 | NPSR1 (0.55) | NPSR1NFKB1BRD4KAT2BBRD9 | |
| SCHEMBL29650380 | 0.79 | NPSR1 (0.86) | NPSR1NFKB1MAPTHTTCYP1A2 | |
| SCHEMBL1009206 | 0.79 | NPSR1 (0.86) | NPSR1NFKB1MAPTHTTCYP1A2 | |
| SCHEMBL30661288 | 0.77 | NPSR1 (0.75) | NPSR1NFKB1MAPTHTTCYP1A2 | |
| SCHEMBL25129316 | 0.77 | ALDH1A1 (0.64) | NPSR1NFKB1MAPTHTTCYP1A2 | |
| SCHEMBL9158496 | 0.77 | NPSR1 (0.82) | NPSR1NFKB1MAPTHTTCYP1A2 | |
| Water SCHEMBL8601146 | 0.77 | NPSR1 (0.82) | NPSR1NFKB1MAPTHTTCYP1A2 | |
| SCHEMBL1922070 | 0.74 | NPSR1 (0.86) | NPSR1NFKB1MAPTHTTCYP1A2 | |
| SCHEMBL10523964 | 0.74 | NPSR1 (0.86) | NPSR1NFKB1MAPTHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455247-B1 | m-Phenylenediamine compound and electrophotosensitive material using said compound | MITA INDUSTRIAL CO LTD (JP) | 1995-09-13 | — | — | EP | disclosed |
| EP-0455247-A2 | m-Phenylenediamine compound and electrophotosensitive material using said compound | MITA INDUSTRIAL CO. LTD. (JP) | 1991-11-06 | — | — | EP | disclosed |