⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9188344 | 1.00 | — | — | |
| SCHEMBL2762585 | 1.00 | — | — | |
| SCHEMBL9265057 | 0.93 | — | — | |
| SCHEMBL9265060 | 0.93 | — | — | |
| SCHEMBL2139086 | 0.93 | — | — | |
| SCHEMBL20863080 | 0.85 | KMT2A (0.39) | — | |
| SCHEMBL5251091 | 0.82 | MAPK1 (0.42) | — | |
| SCHEMBL5250438 | 0.82 | MAPK1 (0.42) | — | |
| Caprolactam SCHEMBL327157 | 0.79 | FKBP5 (0.50) | — | |
| SCHEMBL2598810 | 0.78 | NOS1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118217280-B | Application of daphnetin in pharmaceutical composition for preventing and treating carbapenem-resistant enterobacteria | 青岛农业大学 | 2024-09-17 | — | — | CN | claimed |
| CN-121622671-B | Application of meropenem or aztreonam combined with nalidixic acid in preparation of antibacterial drugs | 山东省妇幼保健院 | 2026-05-15 | — | — | CN | disclosed |
| CN-120058882-B | AraC/XylS family transcription factor and application thereof | 北京大学人民医院 | 2026-02-27 | — | — | CN | disclosed |
| CN-120058882-A | AraC/XylS family transcription factor and application thereof | 北京大学人民医院 | 2025-05-30 | — | — | CN | disclosed |
| CN-118005734-A | Polypeptide resisting carbapenem-resistant enterobacteriaceae bacteria and application thereof | 丽水市中心医院 | 2024-05-10 | — | — | CN | disclosed |
| CN-115252592-B | Application of antihistamine medicine in preparation of antibacterial medicine | 山东省妇幼保健院 | 2023-11-24 | — | — | CN | disclosed |
| CN-106255520-B | Method for removing bacteria from blood using high flow rates | 艾克塞拉医疗公司 | 2022-08-12 | — | — | CN | disclosed |
| EP-0460881-B1 | Process for bicyclic beta-lactams | UNIV NOTRE DAME DU LAC (US) | 1995-11-22 | — | — | EP | disclosed |
| US-5106968-A | Antibiotics | UNIVERSITY OF NOTRE DAME DU LAC COLLEGE OF SCIENCE (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0460881-A1 | Process for bicyclic beta-lactams | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-12-11 | — | — | EP | disclosed |
| US-5051502-A | Process for forming antibiotics | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-09-24 | — | — | US | disclosed |