SCHEMBL9188656

SCHEMBL9188656

CCN(CC)c1cccc(NC(=O)OC)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.69
ALDH1A1 P00352 8/20 0.52
MAPK1 P28482 7/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
NOX1 Q9Y5S8 2/20 0.52
USP2 O75604 1/20 0.52
TP53 P04637 1/20 0.52
PKM P14618 1/20 0.52
TSHR P16473 1/20 0.52
MCL1 Q07820 1/20 0.52
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
CYP3A4 P08684 2/20 0.49
FAAH O00519 1/20 0.48
GFER P55789 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
LMNA P02545 4/20 0.46
HSD17B10 Q99714 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11134313 0.88 MAPK1 (0.61) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL697935 0.84 ALDH1A1 (0.58) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL29594409 0.84 ALDH1A1 (0.58) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL8742796 0.84 SMN1; SMN2 (0.60) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL9352769 0.83 RAB9A (0.66) MAPTALDH1A1MAPK1KMT2ATP53
SCHEMBL8942317 0.83 MAPT (0.54) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL30400187 0.83 RAB9A (0.61) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL9408526 0.83 RAB9A (0.61) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL10388800 0.82 BCHE (0.61) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL11420893 0.81 ALDH1A1 (0.52) MAPTALDH1A1MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0393523-B1 Color developing agent and image forming process FUJI PHOTO FILM CO LTD (JP) 1995-12-13 EP disclosed
US-5310634-A Phenylenediamine derivative FUJI PHOTO FILM CO., LTD. (JP) 1994-05-10 US disclosed
EP-0393523-A2 Color developing agent and image forming process FUJI PHOTO FILM CO., LTD. (JP) 1990-10-24 EP disclosed
EP-0044131-B1 DISPERSE MONOAZO DYESTUFFS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-08-01 EP disclosed
US-4400322-A DICYANOPHENYL PHENYL AZO DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1983-08-23 US disclosed
EP-0044131-A1 Disperse monoazo dyestuffs IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-01-20 EP disclosed
US-4189427-A Azo dyestuffs from benzene diazo component fused to an aliphatic ring and containing two cyano substituents ortho to the azo group BAYER AKTIENGESELLSCHAFT (DE) 1980-02-19 US disclosed
US-RE29834-E PREPARED FROM 4-SULFONYL-1,8-NAPHTHOLACTAMS BAYER AKTIENGESELLSCHAFT (DE) 1978-11-14 US disclosed
US-4048154-A POLYAMIDE FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1977-09-13 US disclosed
US-3978040-A Process for the preparation of cyanoazo compounds by reacting halogenoazo compounds with CuCN in an aqueous media in the presence of a nitrogen base BAYER AKTIENGESELLSCHAFT (DT) 1976-08-31 US disclosed
US-3959310-A BENZINDOLE BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed