Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 5/20 | 0.54 |
| ▸ | NSD2 | O96028 | 4/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.54 |
| ▸ | NT5E | P21589 | 4/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6123733 | 0.84 | CASP6 (0.54) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL4881379 | 0.83 | CASP6 (0.57) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL6205724 | 0.82 | CASP6 (0.55) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL8039912 | 0.81 | CASP6 (0.51) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL9461718 | 0.80 | CASP6 (0.50) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL11125812 | 0.80 | ALDH1A1 (0.56) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL11128939 | 0.79 | ALDH1A1 (0.58) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL1413168 | 0.77 | CASP6 (0.57) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL9009313 | 0.76 | NT5E (0.57) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL13730299 | 0.76 | CASP6 (0.49) | CASP6NSD2DUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451666-A | Reactive dyes having a triazine group which is substituted by hydrogen or an alkyl group | ZENECA LIMITED (GB) | 1995-09-19 | — | — | US | disclosed |
| EP-0578357-A1 | Water soluble reactive dyes | ZENECA LIMITED (GB) | 1994-01-12 | — | — | EP | disclosed |
| US-3933785-A | Azo compounds | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | disclosed |