Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 11/20 | 0.54 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.45 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18040457 | 1.00 | EPHX1 (0.54) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL28905824 | 1.00 | EPHX1 (0.54) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL2782596 | 1.00 | EPHX1 (0.54) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL18040458 | 1.00 | EPHX1 (0.54) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL14682771 | 1.00 | EPHX1 (0.54) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL18040456 | 1.00 | EPHX1 (0.54) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| Hydrochloric Acid SCHEMBL7526117 | 0.98 | EPHX1 (0.52) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| Hydrochloric Acid SCHEMBL4464613 | 0.98 | EPHX1 (0.52) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| Hydrochloric Acid SCHEMBL4478566 | 0.98 | EPHX1 (0.52) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| Hydrochloric Acid SCHEMBL4466381 | 0.98 | EPHX1 (0.52) | EPHX1CASP2ZDHHC20ZDHHC2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101506152-B | Process for producing 1- (3, 4-dichlorobenzyl) -5-octylbiguanide or salt thereof | OTSUKA PHARMA CO LTD | 2012-11-21 | — | — | CN | disclosed |
| US-7868207-B2 | Process for producing 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20090270653-A1 | PROCESS FOR PRODUCING 1-(3,4-DICHLOROBENZYL)-5-OCTYLBIGUANIDE OR A SALT THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-10-29 | — | — | US | disclosed |
| CN-101506152-A | Preparation method of 1-(3, 4-dichlorobenzyl)-5-octyl biguanide or base salt | OTSUKA PHARMA CO LTD (JP) | 2009-08-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270653-A1 | PROCESS FOR PRODUCING 1-(3,4-DICHLOROBENZYL)-5-OCTYLBIGUANIDE OR A SALT THEREOF | SLC6A9, CA9, ALKBH1 | EPHX1 654/4885CASP2 3173/4885ZDHHC20 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.