Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.58 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.58 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9188939 | 1.00 | DPP8 (0.58) | DPP8DPP9TGM2RAB9AIDO1 | |
| Hydrochloric Acid SCHEMBL9187188 | 0.99 | DPP8 (0.57) | DPP8DPP9TGM2RAB9AIDO1 | |
| SCHEMBL9656657 | 0.83 | DPP8 (0.55) | DPP8DPP9TGM2RAB9AALDH1A1 | |
| SCHEMBL9763703 | 0.83 | DPP8 (0.51) | DPP8DPP9RAB9AIDO1ALDH1A1 | |
| SCHEMBL7351737 | 0.83 | DPP8 (0.51) | DPP8DPP9TGM2RAB9AIDO1 | |
| SCHEMBL598314 | 0.82 | DPP8 (0.52) | DPP8DPP9TGM2IDO1HTT | |
| SCHEMBL598313 | 0.82 | DPP8 (0.52) | DPP8DPP9TGM2IDO1HTT | |
| Hydrochloric Acid SCHEMBL10434967 | 0.81 | DPP8 (0.50) | DPP8DPP9RAB9AIDO1ALDH1A1 | |
| SCHEMBL8350753 | 0.81 | RAB9A (0.52) | DPP8DPP9RAB9AIDO1ALDH1A1 | |
| SCHEMBL16949548 | 0.81 | HTR2A (0.52) | DPP8DPP9TGM2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514359-B1 | Alkanoyl L-carnitine amides with aminoacids and pharmaceutical compositions containing same, for promoting regeneration of the nervous tissue, inhibiting neuronal degeneration, enhancing the processes of learning and memory, and for the treatment of coma | SIGMA TAU IND FARMACEUTI (IT) | 1995-09-13 | — | — | EP | disclosed |
| US-5270472-A | Alkanoyl L-carnitine amides with aminoacids and pharmaceutical compositions containing same for promoting regeneration of the nervous tissue, inhibiting neuronal degeneration, enhancing the process of learning and memory and for the treatment of coma | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1993-12-14 | — | — | US | disclosed |
| EP-0514359-A2 | Alkanoyl L-carnitine amides with aminoacids and pharmaceutical compositions containing same, for promoting regeneration of the nervous tissue, inhibiting neuronal degeneration, enhancing the processes of learning and memory, and for the treatment of coma | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1992-11-19 | — | — | EP | disclosed |