Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10434967 | 0.99 | DPP8 (0.50) | DPP8DPP9HTR2AALDH1A1RAB9A | |
| SCHEMBL7351737 | 0.87 | DPP8 (0.51) | DPP8DPP9HTR2ARAB9AIDO1 | |
| SCHEMBL27542540 | 0.85 | IDO1 (0.51) | DPP8DPP9HTR2AALDH1A1RAB9A | |
| SCHEMBL29071562 | 0.84 | POLB (0.50) | HTR2AALDH1A1RAB9AIDO1HTT | |
| SCHEMBL10445821 | 0.84 | DPP8 (0.48) | DPP8DPP9HTR2AALDH1A1RAB9A | |
| SCHEMBL8602149 | 0.83 | HTR2A (0.47) | DPP8DPP9HTR2AALDH1A1RAB9A | |
| SCHEMBL8602153 | 0.83 | HTR2A (0.47) | DPP8DPP9HTR2AALDH1A1RAB9A | |
| SCHEMBL8350753 | 0.83 | RAB9A (0.52) | DPP8DPP9HTR2AALDH1A1RAB9A | |
| SCHEMBL9188944 | 0.83 | DPP8 (0.58) | DPP8DPP9HTR2AALDH1A1RAB9A | |
| SCHEMBL9188939 | 0.83 | DPP8 (0.58) | DPP8DPP9HTR2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021439-A | Senile dementia and memory dysfunction | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-04 | — | — | US | disclosed |