Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865737 | 0.78 | RHEB (0.47) | ARHSD17B10HTTDRD2DRD4 | |
| SCHEMBL11684204 | 0.69 | KDM4E (0.42) | ARHSD17B10HTTDRD2DRD4 | |
| SCHEMBL8855505 | 0.69 | GRIN2D (0.47) | HSD17B10HTTMAPTPOLBTDP1 | |
| SCHEMBL8183601 | 0.68 | HTT (0.56) | HSD17B10HTTDRD2DRD4DRD3 | |
| SCHEMBL2429554 | 0.66 | MAPT (0.44) | ARHSD17B10HTTDRD2DRD4 | |
| SCHEMBL133292 | 0.65 | MAPT (0.50) | HSD17B10HTTDRD2DRD4DRD3 | |
| SCHEMBL5987289 | 0.65 | AR (0.62) | ARHSD17B10HTTMAPTPOLB | |
| SCHEMBL19065022 | 0.63 | HTT (0.53) | HSD17B10HTTDRD2DRD4DRD3 | |
| SCHEMBL11683069 | 0.62 | HSD17B10 (0.60) | ARHSD17B10HTTMAPTPOLB | |
| SCHEMBL9504942 | 0.62 | MEN1 (0.63) | HSD17B10HTTDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667863-A1 | 2-PERHALOGENALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1995-08-23 | — | — | EP | claimed |
| EP-0667863-A1 | 2-PERHALOGENALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |