Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9286966 | 0.81 | TSHR (0.38) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL9188254 | 0.76 | TDP1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL9186665 | 0.75 | CNR2 (0.40) | ALDH1A1LMNA | |
| SCHEMBL14280293 | 0.75 | USP2 (0.52) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL9188680 | 0.74 | SIGMAR1 (0.37) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL9185920 | 0.74 | CA12 (0.41) | TSHRALDH1A1ALOX15 | |
| SCHEMBL795481 | 0.73 | USP2 (0.50) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL2077476 | 0.72 | TSHR (0.55) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL14497716 | 0.72 | USP2 (0.55) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL9190332 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3167168-A | — | — | None | — | — | JP | disclosed |
| EP-0416286-B1 | Sulfonylhydrazines and their use as antineoplastic agents and as antitrypanosomal agents | UNIV YALE (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5214068-A | Anticarcinogenic agents | YALE UNIVERSITY (US) | 1993-05-25 | — | — | US | disclosed |
| US-5101072-A | Anticancer agents, trypanocides | YALE UNIVERSITY (US) | 1992-03-31 | — | — | US | disclosed |
| JP-H03167168-A | SULFONYLHYDRAZINE AND ITS USE AS ANTINEOPLASTIC AGENT AND AS ANTITRYPANOSOMAL AGENT | UNIV YALE | 1991-07-19 | — | — | JP | disclosed |
| EP-0416286-A1 | Sulfonylhydrazines and their use as antineoplastic agents and as antitrypanosomal agents | YALE UNIVERSITY (US) | 1991-03-13 | — | — | EP | disclosed |