Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diallyl Tetrasulfide SCHEMBL389609 | 0.79 | TRPA1 (0.86) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL2987869 | 0.76 | TRPA1 (0.80) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL392677 | 0.76 | TRPA1 (0.80) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL389755 | 0.76 | TRPA1 (0.80) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL24064583 | 0.73 | TRPA1 (0.40) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| Allitridin SCHEMBL562845 | 0.73 | — | — | |
| Allitridin SCHEMBL28776713 | 0.73 | TRPA1 (1.00) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL2931131 | 0.72 | — | — | |
| SCHEMBL2928674 | 0.70 | — | — | |
| SCHEMBL534079 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464521-B1 | Polysulfide compounds and lipid peroxidation inhibitor containing the polysulfide compounds as active ingredient | WAKUNAGA SEIYAKU KK (JP) | 1995-11-29 | — | — | EP | disclosed |
| US-5231114-A | Polysulfides compounds and lipid peroxidation inhibitor containing the polysulfide compounds as active ingredient | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-07-27 | — | — | US | disclosed |
| US-5149879-A | POLYSULFIDES COMPOUNDS AND LIPID PEROXIDATION INHIBITOR CONTAINING THE POLYSULFIDE COMPOUNDS AS ACTIVE INGREDIENT | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0464521-A2 | Polysulfide compounds and lipid peroxidation inhibitor containing the polysulfide compounds as active ingredient | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1992-01-08 | — | — | EP | disclosed |