⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3613047 | 0.83 | — | — | |
| SCHEMBL2561632 | 0.79 | CA2 (0.80) | — | |
| SCHEMBL9396214 | 0.79 | CA2 (0.59) | — | |
| SCHEMBL937637 | 0.78 | CA2 (0.95) | — | |
| SCHEMBL4073463 | 0.78 | CA2 (0.70) | — | |
| SCHEMBL9541712 | 0.77 | — | — | |
| SCHEMBL17100538 | 0.77 | CA2 (0.56) | — | |
| SCHEMBL15319 | 0.77 | — | — | |
| SCHEMBL10665698 | 0.77 | CA2 (0.76) | — | |
| Hydrochloric Acid SCHEMBL27001665 | 0.77 | CA2 (0.76) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2786990-B1 | 2-AMINATED METHYLENE OR 2-ESTERIFIED METHYLENE TANSHINONE DERIVATIVES, AND PREPARATION METHOD AND APPLICATION THEREOF | HANGZHOU BENSHENG PHARMACEUTICAL CO LTD (CN) | 2018-08-08 | — | — | EP | claimed |
| CN-103946217-B | 2-aminated methylene or 2-esterified methylene tanshinone derivatives, and preparation method and application thereof | 杭州本生药业有限公司 | 2017-04-19 | — | — | CN | claimed |
| US-9328083-B2 | 2-aminated methylene or 2-esterified methylene tanshinone derivatives, and preparation method and application thereof | HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD. (CN) | 2016-05-03 | — | — | US | claimed |
| US-20150126552-A1 | 2-AMINATED METHYLENE OR 2-ESTERIFIED METHYLENE TANSHINONE DERIVATIVES, AND PREPARATION METHOD AND APPLICATION THEREOF | HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD. (CN) | 2015-05-07 | — | — | US | claimed |
| EP-2786990-A1 | 2-AMINATED METHYLENE OR 2-ESTERIFIED METHYLENE TANSHINONE DERIVATIVES, AND PREPARATION METHOD AND APPLICATION THEREOF | Hangzhou Bensheng Pharmaceutical Co., Ltd. (CN) | 2014-10-08 | — | — | EP | claimed |
| CN-103946217-A | 2-aminated methylene or 2-esterified methylene tanshinone derivatives, and preparation method and application thereof | HANGZHOU BENSHENG PHARMACEUTICAL CO LTD | 2014-07-23 | — | — | CN | claimed |
| EP-1513814-B1 | NOVEL PIPERIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2010-03-17 | — | — | EP | claimed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | claimed |
| US-RE39707-E1 | Camptothecin derivatives | CATHOLIC HEALTHCARE WEST (US) | 2007-06-26 | — | — | US | claimed |
| US-20050239829-A1 | Novel piperidine compound | TANABE SEIYAKU CO. LTD. (JP) | 2005-10-27 | — | — | US | claimed |
| US-20040142999-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2004-07-22 | — | — | US | claimed |
| US-6350756-B1 | USEFUL FOR TREATING CANCER; (20S) ESTERS WITH AN OXYALKANOIC ACID; | CALIFORNIA PACIFIC MEDICAL CENTER | 2002-02-26 | — | — | US | claimed |
| WO-1998038168-A1 | ISOQUINOLINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 1998-09-03 | — | — | WO | claimed |
| US-5595976-A | ANGIOGENESIS INHIBITOR | ADIR ET COMPAGNIE (FR) | 1997-01-21 | — | — | US | claimed |
| EP-0699679-A1 | Tetrahydropyranyl compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-06 | — | — | EP | claimed |
| EP-0229667-B1 | Peptidylaminodiols | ABBOTT LAB (US) | 1994-07-13 | — | — | EP | claimed |
| EP-0229667-A2 | Peptidylaminodiols | ABBOTT LABORATORIES (US) | 1987-07-22 | — | — | EP | claimed |
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |
| EP-0653427-A1 | Galanthamine derivatives, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-05-17 | — | — | EP | disclosed |
| EP-0137145-B1 | NEW CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1988-04-27 | — | — | EP | disclosed |