Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592538 | 0.90 | NCF1 (0.47) | ALDH1A1NPC1MAPTNCF1CYP1A2 | |
| SCHEMBL6185025 | 0.86 | NCF1 (0.51) | NPC1MAPTNCF1CYP1A2SMN1; SMN2 | |
| SCHEMBL6589199 | 0.85 | HTT (0.47) | ALDH1A1NPC1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL6589107 | 0.84 | CYP1A2 (0.44) | ALDH1A1NPC1MAPTNPSR1NCF1 | |
| SCHEMBL9191404 | 0.84 | BRAF (0.46) | NPC1MAPTNCF1SMN1; SMN2MEN1 | |
| SCHEMBL9391328 | 0.82 | NCF1 (0.40) | NCF1CYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7381173 | 0.81 | GRM2 (0.44) | ALDH1A1MAPTNPSR1NCF1CYP1A2 | |
| SCHEMBL9194078 | 0.81 | MAPT (0.50) | ALDH1A1NPC1MAPTNPSR1CYP1A2 | |
| SCHEMBL6593276 | 0.81 | CYP1A2 (0.41) | ALDH1A1NPC1MAPTNPSR1NCF1 | |
| SCHEMBL9190932 | 0.80 | IGF1R (0.51) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682656-A1 | USE OF PHENYL HETEROARYL UREAS AS 5HT 2C? RECEPTOR ANTAGONISTS AND UREA COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1995-11-22 | — | — | EP | claimed |
| WO-1994018170-A1 | USE OF PHENYL HETEROARYL UREAS AS 5HT2C RECEPTOR ANTAGONISTS AND UREA COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1994-08-18 | — | — | WO | claimed |