Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589107 | 0.89 | CYP1A2 (0.44) | CYP1A2NCF1MEN1KMT2ANPC1 | |
| SCHEMBL7381173 | 0.87 | GRM2 (0.44) | CYP1A2NCF1MEN1KMT2AGRM2 | |
| SCHEMBL6592538 | 0.85 | NCF1 (0.47) | CYP1A2NCF1MEN1KMT2ANPC1 | |
| SCHEMBL6185025 | 0.84 | NCF1 (0.51) | CYP1A2NCF1MEN1KMT2ANPC1 | |
| SCHEMBL9190817 | 0.81 | ALDH1A1 (0.43) | CYP1A2NCF1MEN1KMT2ANPC1 | |
| SCHEMBL9190932 | 0.80 | IGF1R (0.51) | MEN1KMT2AGRM2SMN1; SMN2HTT | |
| SCHEMBL6589199 | 0.78 | HTT (0.47) | MEN1KMT2ANPC1RAB9AGRM2 | |
| SCHEMBL7378778 | 0.78 | KDM1A (0.41) | CYP1A2NCF1MEN1KMT2ANPC1 | |
| SCHEMBL9391328 | 0.78 | NCF1 (0.40) | CYP1A2NCF1MEN1KMT2ARAB9A | |
| SCHEMBL9191404 | 0.77 | BRAF (0.46) | NCF1MEN1KMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150977-B1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2004-08-25 | — | — | EP | claimed |