Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184907 | 0.86 | PPARG (0.43) | PPARGEPHX2HDAC8HDAC6HDAC11 | |
| SCHEMBL9185687 | 0.85 | PPARG (0.42) | PPARGEPHX2HDAC8HDAC6HDAC11 | |
| SCHEMBL9188431 | 0.85 | PPARG (0.42) | PPARGEPHX2HDAC8HDAC6HDAC11 | |
| SCHEMBL9188453 | 0.84 | PPARG (0.45) | PPARGEPHX2PLA2G4A | |
| SCHEMBL9188617 | 0.84 | PPARG (0.43) | PPARGEPHX2HDAC8HDAC6HDAC11 | |
| SCHEMBL9186891 | 0.84 | PPARG (0.45) | PPARGEPHX2PLA2G4A | |
| SCHEMBL9189437 | 0.83 | PLA2G4A (0.40) | PPARGEPHX2HDAC8HDAC6HDAC11 | |
| SCHEMBL9188860 | 0.83 | ITGB3 (0.47) | PPARGEPHX2HDAC8HDAC6HDAC11 | |
| SCHEMBL9184540 | 0.83 | PPARG (0.43) | PPARGEPHX2HDAC8HDAC6HDAC11 | |
| SCHEMBL9185683 | 0.83 | KCNQ3 (0.46) | PPARGEPHX2HDAC8HDAC6HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476935-B1 | New indol and indoline derivatives | LILLY INDUSTRIES LTD (GB) | 1995-07-26 | — | — | EP | disclosed |
| US-5185361-A | Indole sulfonamides; Leukotriene antagonists | LILLY INDUSTRIES LIMITED (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0476935-A1 | New indol and indoline derivatives | LILLY INDUSTRIES LIMITED (GB) | 1992-03-25 | — | — | EP | disclosed |