Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113895 | 0.83 | TDP1 (0.39) | PLA2G4AKDM4EMAPK1HIF1APLA2G2A | |
| SCHEMBL1525045 | 0.81 | KDM4E (0.64) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL224483 | 0.76 | EPHX1 (0.54) | PLA2G4APLA2G2AEPHX2 | |
| SCHEMBL5307349 | 0.75 | KDM4E (0.37) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL25065006 | 0.74 | KDM4E (0.68) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL30439276 | 0.74 | PLA2G2A (0.67) | PLA2G4APLA2G2AMEN1KMT2ADPP7 | |
| SCHEMBL19658369 | 0.73 | KDM4E (0.46) | PLA2G4AKDM4EMAPK1HIF1APLA2G2A | |
| SCHEMBL29371504 | 0.73 | PRMT1 (0.56) | KDM4EMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL608623 | 0.73 | KDM4E (0.73) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL22984077 | 0.73 | KDM4E (0.73) | KDM4EMAPK1HIF1APAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470833-A | Vasodilators, bronchodilators | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |