SCHEMBL919089

SCHEMBL919089

CCCCc1ccc(N(c2ccc(CCCC)cc2)c2ccc(-c3ccc(-c4ccc(N(c5ccc(C(C)C)cc5)c5ccc(C(C)C)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
UCHL3 P15374 2/20 0.53
RARB P10826 6/20 0.46
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
AKR1C2 P52895 1/20 0.43
AKR1C1 Q04828 1/20 0.43
NISCH Q9Y2I1 1/20 0.42
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
RARA P10276 1/20 0.41
MAPT P10636 1/20 0.41
MTOR P42345 1/20 0.41
KMT2A Q03164 1/20 0.41
FDFT1 P37268 1/20 0.40
CNR2 P34972 1/20 0.40
HSD11B1 P28845 1/20 0.40
HTR2A P28223 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258104 1.00 UCHL3 (0.53) UCHL3RARBCA1CA2AKR1C2
SCHEMBL13701260 0.91 UCHL3 (0.47) UCHL3RARBCA1CA2AKR1C2
SCHEMBL3669327 0.91 UCHL3 (0.60) UCHL3RARBCA1CA2AKR1C2
SCHEMBL917953 0.88 RARB (0.56) RARBCA1CA2NISCHTSHR
SCHEMBL25907712 0.87 UCHL3 (0.45) UCHL3CA1CA2HSD17B10ALDH1A1
SCHEMBL12018269 0.87 UCHL3 (0.45) UCHL3CA1CA2HSD17B10ALDH1A1
SCHEMBL8090819 0.86 UCHL3 (0.56) UCHL3RARBCA1CA2HSD17B10
SCHEMBL13015006 0.84 KCNH2 (0.46) UCHL3CA1CA2TSHRCNR2
SCHEMBL11887122 0.84 RARB (0.56) RARBCA1CA2NISCHTSHR
SCHEMBL11887128 0.83 CA2 (0.46) UCHL3CA1CA2HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2290452-B1 POSS melamine overcoated photoconductors XEROX CORP (US) 2016-06-01 EP claimed
US-7871746-B2 Thiophthalimides containing photoconductors XEROX CORPORATION (US) 2011-01-18 US disclosed
US-20080268359-A1 Single layered photoconductors XEROX CORPORATION 2008-10-30 US disclosed