SCHEMBL9192017

SCHEMBL9192017

CON1C(C)(C)CC(OC(=O)CCSSCCC(=O)OC2CC(C)(C)N(OC)C(C)(C)C2)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.34
ESR1 P03372 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TP53 P04637 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7476147 0.89 TSHR (0.39) KMT2AMEN1GAATSHRALDH1A1
SCHEMBL22585044 0.86 TSHR (0.39) KMT2AMEN1GAATSHRALDH1A1
SCHEMBL7471002 0.84 NAAA (0.45) KMT2AMEN1GAATSHRALDH1A1
SCHEMBL22585045 0.84 TSHR (0.47) KMT2AMEN1GAATSHRALDH1A1
SCHEMBL24915180 0.83 KMT2A (0.39) KMT2AMEN1GAATSHRALDH1A1
SCHEMBL13554328 0.83 GAA (0.41) KMT2AMEN1GAATSHRALDH1A1
SCHEMBL17281376 0.82 TSHR (0.39) KMT2AMEN1GAATSHRALDH1A1
SCHEMBL24914859 0.82 ALDH1A1 (0.36) KMT2AMEN1GAATSHRALDH1A1
SCHEMBL19009135 0.80 TSHR (0.38) KMT2AMEN1GAATSHRALDH1A1
SCHEMBL9195823 0.80 TSHR (0.38) KMT2AMEN1GAATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389424-B1 1-Hydrocarbyloxy hindered amine mercaptoacid esters, thioacetals, sulfides and disulfides CIBA GEIGY AG (CH) 1995-06-07 EP claimed
US-5026750-A Photostabilizers for polymer substrates CIBA-GEIGY CORPORATION (US) 1991-06-25 US claimed
EP-0389424-A1 1-Hydrocarbyloxy hindered amine mercaptoacid esters, thioacetals, sulfides and disulfides CIBA-GEIGY AG (CH) 1990-09-26 EP claimed
EP-0389424-B1 1-Hydrocarbyloxy hindered amine mercaptoacid esters, thioacetals, sulfides and disulfides CIBA GEIGY AG (CH) 1995-06-07 EP disclosed
US-5026750-A Photostabilizers for polymer substrates CIBA-GEIGY CORPORATION (US) 1991-06-25 US disclosed
EP-0389424-A1 1-Hydrocarbyloxy hindered amine mercaptoacid esters, thioacetals, sulfides and disulfides CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed