Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10896403 | 0.82 | LMNA (0.59) | SLC1A1TSHRLMNAKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL11075984 | 0.80 | LMNA (0.57) | SLC1A1TSHRLMNAKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL10962020 | 0.80 | LMNA (0.57) | SLC1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL9843547 | 0.80 | SLC1A1 (0.33) | SLC1A1LMNAMAPTCYP2D6NFKB1 | |
| SCHEMBL4957134 | 0.78 | — | — | |
| SCHEMBL2217142 | 0.78 | TSHR (0.57) | SLC1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL7064658 | 0.77 | TSHR (0.50) | SLC1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL12534353 | 0.77 | TSHR (0.50) | SLC1A1TSHRLMNAKDM4EKMT2A | |
| SCHEMBL24804137 | 0.76 | — | — | |
| SCHEMBL18116498 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2017643-A | — | — | None | — | — | JP | disclosed |
| EP-0688314-A1 | PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994021604-A1 | PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-29 | — | — | WO | disclosed |
| JP-H0217643-A | METAL LIFT-OFF METHOD | INTERNATL BUSINESS MACH CORP <IBM> | 1990-01-22 | — | — | JP | disclosed |