Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934006 | 0.81 | DPP4 (0.31) | — | |
| SCHEMBL26647503 | 0.78 | — | — | |
| SCHEMBL7808679 | 0.73 | — | — | |
| SCHEMBL13730392 | 0.69 | MAPK1 (0.33) | ALDH1A1 | |
| SCHEMBL31178410 | 0.69 | MEN1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL14354070 | 0.69 | — | — | |
| SCHEMBL9432129 | 0.68 | F2RL3 (0.33) | ALDH1A1ALOX15TSHR | |
| SCHEMBL7935980 | 0.68 | GAA (0.40) | ALDH1A1 | |
| SCHEMBL24978005 | 0.67 | LRRK2 (0.35) | ALDH1A1 | |
| SCHEMBL8873230 | 0.66 | LRRK2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445644-B1 | Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation | BASF AG (DE) | 1995-05-24 | — | — | EP | disclosed |
| US-5237063-A | TRIFLUORO- AND CHLORODIFLUOROMETHOXYPYRIMIDINES AND THE PREPARATION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | disclosed |
| EP-0445644-A1 | Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |