SCHEMBL9432129

SCHEMBL9432129

FC(F)Oc1cc(OC(F)F)nc(Cl)n1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 1/20 0.33
ALDH1A1 P00352 2/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9433456 0.90 ALDH1A1 (0.41) F2RL3ALDH1A1HTT
SCHEMBL9432361 0.86 ALDH1A1 (0.49) F2RL3ALDH1A1TSHRHTT
SCHEMBL13012204 0.76 PDE2A (0.35) F2RL3
SCHEMBL22576042 0.76 MAPT (0.38) ALDH1A1ALOX15TSHRHTT
SCHEMBL1577067 0.76 NUDT1 (0.37) ALDH1A1
SCHEMBL25231249 0.73 F2RL3 (0.35) F2RL3ALDH1A1TSHRHTT
SCHEMBL10748211 0.73 KMT2A (0.50) ALDH1A1
SCHEMBL16579756 0.73 F2RL3 (0.38) F2RL3ALDH1A1TSHRHTT
SCHEMBL10762791 0.71 TDP1 (0.34) ALDH1A1TSHRHTT
SCHEMBL7586002 0.71 KMT2A (0.39) ALDH1A1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5284820-A Herbicidal substituted cycloalkenes BAYER AKTIENGESELLSCHAFT (DE) 1994-02-08 US disclosed
EP-0532948-A1 Substituted cycloalkenes as herbicides BAYER AG (DE) 1993-03-24 EP disclosed