SCHEMBL7808679

SCHEMBL7808679

Fc1nc(F)c(OC(F)F)c(Cl)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9192068 0.73 ALDH1A1 (0.33)
SCHEMBL7934006 0.70 DPP4 (0.31)
SCHEMBL7925330 0.69 GAA (0.36)
SCHEMBL9414552 0.68 KEAP1 (0.32)
SCHEMBL8581211 0.64
SCHEMBL9178065 0.64
SCHEMBL14354070 0.63
SCHEMBL13730392 0.63 MAPK1 (0.33)
SCHEMBL9009790 0.61 PDE10A (0.34)
SCHEMBL7932063 0.61 KDM4E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0445644-B1 Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation BASF AG (DE) 1995-05-24 EP claimed
US-5237063-A TRIFLUORO- AND CHLORODIFLUOROMETHOXYPYRIMIDINES AND THE PREPARATION THEREOF BASF AKTIENGESELLSCHAFT (DE) 1993-08-17 US claimed
US-6235904-B1 VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. BASF AKTIENGESELLSCHAFT (DE) 2001-05-22 US disclosed
EP-0572429-B1 SULFONYL UREA DERIVATES, METHOD FOR PREPARING THEM AND USE THEREOF BASF AG (DE) 2001-04-18 EP disclosed
US-5591694-A COMPOUND USED TO CONTROL UNDESIRABLE PLANT GROWTH BASF AKTIENGESELLSCHAFT (DE) 1997-01-07 US disclosed
EP-0446743-B1 Herbicidal sulfonylureas, process for their preparation and intermediates BASF AG (DE) 1995-08-02 EP disclosed
US-5434124-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1995-07-18 US disclosed
EP-0445642-B1 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation BASF AG (DE) 1995-07-12 EP disclosed
EP-0445644-B1 Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation BASF AG (DE) 1995-05-24 EP disclosed
EP-0600967-B1 HERBICIDAL SULPHONYL UREAS, PROCESS AND INTERMEDIATES FOR PRODUCING THE SAME BASF AG (DE) 1995-04-19 EP disclosed
EP-0600967-A1 HERBICIDAL SULPHONYL UREAS, PROCESS AND INTERMEDIATES FOR PRODUCING THE SAME. BASF AG (DE) 1994-06-15 EP disclosed
US-5283332-A 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof BASF AKTIENGESELLSCHAFT (DE) 1994-02-01 US disclosed
US-5276007-A Herbicidal sulfonylureas BASF AKTIENGESELLSCHAFT (DE) 1994-01-04 US disclosed
EP-0572429-A1 SULFONYL UREA DERIVATES, METHOD FOR PREPARING THEM AND USE THEREOF BASF Aktiengesellschaft (DE) 1993-12-08 EP disclosed
US-5237063-A TRIFLUORO- AND CHLORODIFLUOROMETHOXYPYRIMIDINES AND THE PREPARATION THEREOF BASF AKTIENGESELLSCHAFT (DE) 1993-08-17 US disclosed
WO-1993005048-A2 HERBICIDAL SULPHONYL UREAS, PROCESS AND INTERMEDIATES FOR PRODUCING THE SAME BASF AKTIENGESELLSCHAFT (DE) 1993-03-18 WO disclosed
WO-1992014715-A1 SULFONYL UREA DERIVATES, METHOD FOR PREPARING THEM AND USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1992-09-03 WO disclosed
EP-0446743-A2 Herbicidal sulfonylureas, process for their preparation and intermediates BASF Aktiengesellschaft (DE) 1991-09-18 EP disclosed
EP-0445642-A1 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation BASF Aktiengesellschaft (DE) 1991-09-11 EP disclosed
EP-0445644-A1 Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation BASF Aktiengesellschaft (DE) 1991-09-11 EP disclosed