Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185515 | 0.91 | ALDH1A1 (0.71) | ALDH1A1TSHRSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL755347 | 0.89 | ALDH1A1 (0.69) | ALDH1A1TSHRSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL17459104 | 0.88 | ALDH1A1 (0.67) | ALDH1A1TSHRSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL28461120 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TSHRSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL711863 | 0.80 | ALDH1A1 (0.57) | ALDH1A1TSHRSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL21866493 | 0.80 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2LMNAMAPK1L3MBTL1 | |
| SCHEMBL10657445 | 0.80 | PTPN2 (0.42) | ALDH1A1TSHRSMN1; SMN2L3MBTL1SLC6A2 | |
| SCHEMBL9195902 | 0.79 | PKM (0.51) | ALDH1A1TSHRSMN1; SMN2L3MBTL1TDP1 | |
| E1501 SCHEMBL14031569 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TSHRSMN1; SMN2LMNAMAPK1 | |
| E1501 SCHEMBL901210 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TSHRSMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448006-B1 | Process for the preparation of acylales | HOECHST AG (DE) | 1995-01-25 | — | — | EP | disclosed |
| US-5231221-A | PROCESS FOR THE PREPARATION OF ACYLALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |
| EP-0448006-A2 | Process for the preparation of acylales | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-25 | — | — | EP | disclosed |