Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 9/20 | 0.35 |
| ▸ | GABRD | O14764 | 9/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 9/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 9/20 | 0.35 |
| ▸ | GABRE | P78334 | 9/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198111 | 0.93 | SMN1; SMN2 (0.36) | SMN1; SMN2NPC1MAPTHTTRAB9A | |
| SCHEMBL9193483 | 0.87 | GABRB3 (0.48) | SMN1; SMN2LMNAGABRPGABRDGABRA1 | |
| SCHEMBL2839567 | 0.87 | GABRP (0.35) | SMN1; SMN2NPC1MAPTHTTRAB9A | |
| SCHEMBL2836868 | 0.85 | GABRP (0.44) | SMN1; SMN2MAPTLMNAGABRPGABRD | |
| SCHEMBL9197753 | 0.83 | DDR1 (0.34) | SMN1; SMN2NPC1MAPTHTTRAB9A | |
| SCHEMBL2837065 | 0.83 | GABRP (0.34) | SMN1; SMN2NPC1MAPTHTTRAB9A | |
| SCHEMBL2835096 | 0.82 | GABRB3 (0.34) | SMN1; SMN2LMNAGABRPGABRDGABRA1 | |
| SCHEMBL9192680 | 0.81 | GABRB3 (0.49) | SMN1; SMN2LMNAGABRPGABRDGABRA1 | |
| SCHEMBL9193418 | 0.81 | DDR1 (0.34) | SMN1; SMN2NPC1MAPTHTTRAB9A | |
| SCHEMBL9191270 | 0.81 | GABRP (0.38) | SMN1; SMN2NPC1MAPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385809-B1 | Pesticidal 3-cyano-5-alkoxy-1-arylpyrazoles | RHONE POULENC AGROCHIMIE (FR) | 1995-07-05 | — | — | EP | claimed |
| EP-0385809-B1 | Pesticidal 3-cyano-5-alkoxy-1-arylpyrazoles | RHONE POULENC AGROCHIMIE (FR) | 1995-07-05 | — | — | EP | disclosed |
| EP-0385809-A1 | Pesticidal 3-cyano-5-alkoxy-1-arylpyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1990-09-05 | — | — | EP | disclosed |