Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410155 | 0.91 | CNR2 (0.37) | KDM4EALDH1A1CNR2PARP1VCP | |
| SCHEMBL10410420 | 0.85 | CNR2 (0.38) | KDM4EALDH1A1CNR2PARP1VCP | |
| SCHEMBL2338995 | 0.81 | CNR2 (0.36) | KDM4EALDH1A1CNR2 | |
| SCHEMBL20180706 | 0.80 | CNR2 (0.38) | KDM4EALDH1A1CNR2 | |
| SCHEMBL10583284 | 0.79 | CNR2 (0.35) | KDM4EALDH1A1CNR2 | |
| SCHEMBL9218122 | 0.78 | F2 (0.35) | KDM4EALDH1A1CNR2 | |
| SCHEMBL9369711 | 0.77 | PARP1 (0.35) | PARP1VCPGABRPGABRDGABRA1 | |
| SCHEMBL19884277 | 0.76 | CNR2 (0.36) | KDM4EALDH1A1CNR2 | |
| SCHEMBL10410349 | 0.75 | CNR2 (0.36) | KDM4EALDH1A1CNR2PARP1GABRP | |
| SCHEMBL351540 | 0.73 | GABRP (0.46) | KDM4EALDH1A1PARP1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584470-B1 | Process for the preparation of 2,3-pyridinedicarboxylic acids from 3-(2-imidazolin-2-yl)picolinic acids | AMERICAN CYANAMID CO (US) | 1995-08-16 | — | — | EP | disclosed |
| EP-0584470-A1 | Process for the preparation of 2,3-pyridinedicarboxylic acids from 3-(2-imidazolin-2-yl)picolinic acids | AMERICAN CYANAMID COMPANY (US) | 1994-03-02 | — | — | EP | disclosed |
| US-5250694-A | Process for the preparation of 2,3-pyridine-dicarboxylic acids from 3-(2-imidazolin-2-yl)picolinic acids | AMERICAN CYANAMID COMPANY (US) | 1993-10-05 | — | — | US | disclosed |