SCHEMBL351540

SCHEMBL351540

CCc1cnc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 3/20 0.46
GABRD O14764 3/20 0.46
GABRA1 P14867 3/20 0.46
GABRB1 P18505 3/20 0.46
GABRG2 P18507 3/20 0.46
GABRB3 P28472 3/20 0.46
GABRA5 P31644 3/20 0.46
GABRA3 P34903 3/20 0.46
GABRA2 P47869 3/20 0.46
GABRB2 P47870 3/20 0.46
GABRA4 P48169 3/20 0.46
GABRE P78334 3/20 0.46
GABRA6 Q16445 3/20 0.46
GABRG1 Q8N1C3 3/20 0.46
GABRG3 Q99928 3/20 0.46
GABRQ Q9UN88 3/20 0.46
PARP1 P09874 1/20 0.42
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3086345 0.98 GABRP (0.45) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL3086351 0.98 GABRP (0.45) GABRPGABRDGABRA1GABRB1GABRG2
Nitric Acid SCHEMBL7049249 0.91 GABRP (0.40) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL9632787 0.89 GABRP (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL9630611 0.88 GABRP (0.42) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28965796 0.86 DHODH (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29619789 0.86 DHODH (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL9839363 0.86 SMN1; SMN2 (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28983538 0.85 KDM4E (0.48) RAB9ASMN1; SMN2NPC1KDM4EALDH1A1
SCHEMBL30924884 0.85 CYP2C9 (0.46) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 558 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2026-02-12 US claimed
EP-4680369-A1 SYSTEMS FOR CARBON DIOXIDE CAPTURE USING FUNCTIONALIZED SORBENTS AND WATER MANAGEMENT GE Vernova Technology GmbH (CH) 2026-01-21 EP claimed
US-20250354659-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION NUOVO PIGNONE TECNOLOGIE – S R L (IT) 2025-11-20 US claimed
WO-2025238576-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION Nuovo Pignone Tecnologie – S.r.l. (IT) 2025-11-20 WO claimed
EP-4572884-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP General Electric Technology GmbH (CH) 2025-06-25 EP claimed
EP-4556112-A2 SORBENT COMPOSITIONS, SYSTEMS, AND METHODS General Electric Technology GmbH (CH) 2025-05-21 EP claimed
CN-119869460-A Sorbent compositions, systems, and methods 通用电气技术有限公司 2025-04-25 CN claimed
WO-2024232872-A1 SYSTEMS FOR CARBON DIOXIDE CAPTURE USING FUNCTIONALIZED SORBENTS AND WATER MANAGEMENT GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2024-11-14 WO claimed
US-20240199653-A1 METHOD FOR FORMING AN ELECTRICALLY CONDUCTIVE METAL ORGANIC FRAMEWORK COMPOSITE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-06-20 US claimed
WO-2024123903-A1 SORBENT COMPOSITIONS, SYSTEMS, AND METHODS GE INFRASTRUCTURE TECHNOLOGY LLC (US) 2024-06-13 WO claimed
CN-1057456-A Prepare pyridine-2 by the dichloro-dialkyl maleate, the method for 3-dicarboxylic acid dialkyl esters and derivative thereof AMERICAN CYANAMID CO (US) 1992-01-01 CN claimed
CN-1057455-A Prepare pyridine-2 by dichloro succinate dialkyl ester, the method for 3-dicarboxylic acid dialkyl esters and derivative thereof AMERICAN CYANAMID CO (US) 1992-01-01 CN claimed
EP-0461403-A1 Process for the preparation of dialkyl pyridine-2,3-dicarboxylate and derivatives thereof from dialkyl dichlorosucciante AMERICAN CYANAMID COMPANY (US) 1991-12-18 EP claimed
EP-0461401-A1 Process for the preparation of dialkyl, pyridine-2,3-dicarboxylates and derivatives thereof from dialkyl dichloromaleate AMERICAN CYANAMID COMPANY (US) 1991-12-18 EP claimed
EP-0461402-A1 Process for the preparation of substituted and unsubstituted 2,3-pyridinedicarboxylates from chloromaleate or chlorofumarate or mixtures thereof AMERICAN CYANAMID COMPANY (US) 1991-12-18 EP claimed
EP-0259687-B1 METHOD FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC ACIDS AMERICAN CYANAMID COMPANY (US) 1991-07-03 EP claimed
EP-0220518-B1 PREPARATION OF SUBSTITUTED AND DISUBSTITUTED PYRIDINE-2,3-DICARBOXYLATE ESTERS AMERICAN CYANAMID COMPANY (US) 1991-02-06 EP claimed
EP-0331899-A2 A method for the sequential oxidation of substituted-8-hydroxy-quinolines to produce substituted-pyridine-2,3-dicarboxylic acids AMERICAN CYANAMID COMPANY (US) 1989-09-13 EP claimed
US-4816588-A OXIDATION OF 8-SUBSTITUTED QUINOLINES AMERICAN CYANAMID COMPANY (US) 1989-03-28 US claimed
EP-0259687-A2 Method for the preparation of pyridine-2,3-dicarboxylic acids AMERICAN CYANAMID COMPANY (US) 1988-03-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP SRMS, TYRO3, SELE GABRP 3641/4885GABRD 3918/4885GABRA1 2794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.