SCHEMBL9192736

SCHEMBL9192736

CCCCC(c1ccccc1)c1cc(O)ccc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.48
MAPT P10636 3/20 0.48
CHRM2 P08172 2/20 0.48
CHRM5 P08912 2/20 0.48
CHRM1 P11229 2/20 0.48
CHRM3 P20309 2/20 0.48
HRH1 P35367 2/20 0.48
OPRK1 P41145 2/20 0.48
ESR1 P03372 1/20 0.48
CHRM4 P08173 1/20 0.48
KCNE1 P15382 1/20 0.48
PTGS1 P23219 1/20 0.48
HRH2 P25021 1/20 0.48
HTR2A P28223 1/20 0.48
SLC6A4 P31645 1/20 0.48
ADRA1A P35348 1/20 0.48
KCNQ1 P51787 1/20 0.48
KCNH2 Q12809 1/20 0.48
CACNA1C Q13936 1/20 0.48
SCN5A Q14524 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9193705 0.85 TYR (0.51) LMNAMAPTCHRM2CHRM5CHRM1
SCHEMBL11807384 0.85 LMNA (0.46) LMNAMAPTCHRM2CHRM5CHRM1
SCHEMBL1841355 0.83 TSHR (0.48) LMNAMAPTCHRM2CHRM5CHRM1
SCHEMBL29492449 0.83 TYR (0.55) LMNAMAPTOPRK1HPGDNPSR1
SCHEMBL21830489 0.83 TYR (0.55) LMNAMAPTOPRK1HPGDNPSR1
SCHEMBL27703049 0.83 TSHR (0.44) LMNAMAPTCHRM2CHRM5CHRM1
SCHEMBL11797183 0.82 BCHE (0.46) LMNAMAPTCHRM2CHRM5CHRM1
SCHEMBL11801478 0.81 LMNA (0.46) LMNAMAPTCHRM2CHRM5CHRM1
SCHEMBL27514441 0.80 CHRM3 (0.64) LMNAMAPTCHRM2CHRM5CHRM1
SCHEMBL7517085 0.80 SIGMAR1 (0.50) LMNAMAPTCHRM2CHRM1HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037940-A Hydroquinone, isophthalic or terephthaic acid, and a substituted hydroquinone; electrical electronic and auto parts IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1991-08-06 US claimed
EP-0399512-B1 Wholly aromatic copolyester IDEMITSU PETROCHEMICAL CO (JP) 1995-10-18 EP disclosed
EP-0375960-B1 Thermoplastic, liquid-crystalline, wholly aromatic polyimide ester and method of producing the same IDEMITSU PETROCHEMICAL CO (JP) 1994-03-30 EP disclosed
US-5120820-A Injection molding materials having dimensional stability and accuracy; fluid flow; electronic and automobile parts IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-06-09 US disclosed
US-5109100-A Polyeserimide copolymer; dimensional stability IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-04-28 US disclosed
US-5037940-A Hydroquinone, isophthalic or terephthaic acid, and a substituted hydroquinone; electrical electronic and auto parts IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1991-08-06 US disclosed
EP-0399512-A2 Wholly aromatic copolyester IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-11-28 EP disclosed
EP-0375960-A1 Thermoplastic, liquid-crystalline, wholly aromatic polyimide ester and method of producing the same IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-07-04 EP disclosed