Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13700812 | 1.00 | HRH3 (0.41) | HRH3LPLLIPGRXRARXRB | |
| SCHEMBL919282 | 0.93 | HRH3 (0.46) | HRH3LPLLIPGNISCHEGFR | |
| SCHEMBL10062463 | 0.93 | HRH3 (0.46) | HRH3LPLLIPGNISCHEGFR | |
| SCHEMBL19423242 | 0.88 | RXRA (0.48) | HRH3LPLLIPGRXRARXRB | |
| SCHEMBL27043233 | 0.86 | RXRA (0.36) | HRH3LPLLIPGRXRARXRB | |
| SCHEMBL12304289 | 0.85 | LPL (0.52) | LPLLIPGTSHRMAPK1ATM | |
| SCHEMBL3896543 | 0.85 | LPL (0.52) | LPLLIPGTSHRMAPK1ATM | |
| SCHEMBL12533875 | 0.84 | HCRTR2 (0.41) | HRH3LPLLIPGNISCHEGFR | |
| SCHEMBL1702645 | 0.84 | TP53 (0.54) | HRH3LPLLIPGNISCHTSHR | |
| SCHEMBL13855250 | 0.84 | TP53 (0.54) | TSHRTDP1L3MBTL1TP53TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428214-B1 | Electrophotographic recording material | AGFA GEVAERT NV (BE) | 1995-03-29 | — | — | EP | disclosed |
| EP-0393787-B1 | Electrophotographic recording material | AGFA GEVAERT NV (BE) | 1995-02-15 | — | — | EP | disclosed |
| US-5145759-A | Conductive support, negatively chargeable photoconductive layer containing insulating polymeric binder with pigment and charge transport substance | AGFA-GEVAERT, N.V. (BE) | 1992-09-08 | — | — | US | disclosed |
| EP-0428214-A1 | Electrophotographic recording material | AGFA-GEVAERT N.V. (BE) | 1991-05-22 | — | — | EP | disclosed |
| EP-0393787-A2 | Electrophotographic recording material | AGFA-GEVAERT N.V. (BE) | 1990-10-24 | — | — | EP | disclosed |