SCHEMBL9194397

SCHEMBL9194397

Fc1nc(OC(F)(F)F)c(F)c(OC(F)(F)F)n1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MPL P40238 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9192104 0.77
SCHEMBL7804014 0.70
SCHEMBL9189909 0.62
SCHEMBL7798088 0.62 MPL (0.32) MPL
SCHEMBL7806791 0.62 NPC1 (0.32)
SCHEMBL9196363 0.62 ALDH1A1 (0.33)
SCHEMBL7808644 0.60 CA12 (0.34)
SCHEMBL31171303 0.59 CA1 (0.32)
SCHEMBL17655239 0.59
SCHEMBL31523674 0.58 MPL (0.39) MPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0445644-B1 Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation BASF AG (DE) 1995-05-24 EP disclosed
US-5237063-A TRIFLUORO- AND CHLORODIFLUOROMETHOXYPYRIMIDINES AND THE PREPARATION THEREOF BASF AKTIENGESELLSCHAFT (DE) 1993-08-17 US disclosed
EP-0445644-A1 Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation BASF Aktiengesellschaft (DE) 1991-09-11 EP disclosed