Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195795 | 0.84 | NPC1 (0.42) | KMT2AMAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL9193831 | 0.79 | MEN1 (0.49) | KMT2AMAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL9196684 | 0.78 | MAPT (0.44) | KMT2AMAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL9194003 | 0.77 | MAPT (0.49) | KMT2AMAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL2678410 | 0.76 | SMN1; SMN2 (0.51) | KMT2AMAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL9191911 | 0.72 | LMNA (0.50) | KMT2AMAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL9192944 | 0.72 | KMT2A (0.55) | KMT2AMAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL9192170 | 0.72 | BCHE (0.47) | KMT2AMAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL20553753 | 0.72 | SMN1; SMN2 (0.50) | KMT2AMAPTMEN1CYP1A2CYP2D6 | |
| SCHEMBL9196268 | 0.72 | MAPT (0.50) | KMT2AMAPTMEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443474-B1 | 1-Phenoxycarbonyl-2-pyrrolidinone derivatives and nootropic agents | NISSHIN FLOUR MILLING CO (JP) | 1995-08-16 | — | — | EP | disclosed |
| US-5140041-A | Cognition activators, for treatment of Alzheimer's disease | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| EP-0443474-A2 | 1-Phenoxycarbonyl-2-pyrrolidinone derivatives and nootropic agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |