Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191911 | 0.83 | LMNA (0.50) | BCHECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9196684 | 0.83 | MAPT (0.44) | CYP1A2CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL9192944 | 0.83 | KMT2A (0.55) | BCHECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9190580 | 0.82 | MAPT (0.49) | BCHETRPA1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2678410 | 0.82 | SMN1; SMN2 (0.51) | CYP1A2CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL9193440 | 0.79 | KMT2A (0.57) | CYP2C9CYP2C19KMT2AMEN1MAPT | |
| SCHEMBL28137837 | 0.78 | TRPA1 (0.61) | BCHETRPA1CYP1A2CYP2C19KMT2A | |
| SCHEMBL20553753 | 0.78 | SMN1; SMN2 (0.50) | CYP1A2CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL32666095 | 0.77 | SMN1; SMN2 (0.51) | CYP1A2CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL9191187 | 0.74 | BCHE (0.46) | BCHECYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443474-B1 | 1-Phenoxycarbonyl-2-pyrrolidinone derivatives and nootropic agents | NISSHIN FLOUR MILLING CO (JP) | 1995-08-16 | — | — | EP | disclosed |
| US-5227395-A | ANTI-PLATELET AGGREGATING AGENT | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| US-5140041-A | Cognition activators, for treatment of Alzheimer's disease | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| EP-0443474-A2 | 1-Phenoxycarbonyl-2-pyrrolidinone derivatives and nootropic agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |