⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL919510 | 0.78 | SMPD1 (0.38) | — | |
| SCHEMBL7045716 | 0.77 | — | — | |
| SCHEMBL537766 | 0.75 | THRB (0.32) | — | |
| SCHEMBL8853322 | 0.75 | THRB (0.32) | — | |
| SCHEMBL7037706 | 0.72 | — | — | |
| SCHEMBL11598998 | 0.71 | — | — | |
| SCHEMBL3148926 | 0.67 | — | — | |
| SCHEMBL486485 | 0.67 | TSHR (0.31) | — | |
| SCHEMBL142052 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL11601906 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026103904-A1 | 4-AMINO SUBSTITUTED PYRIDAZINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2026-05-21 | — | — | WO | disclosed |
| CN-119585261-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |
| US-20250034187-A1 | STING AGONISTIC COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-01-30 | — | — | US | disclosed |
| CN-119365459-A | Polycyclic compounds as KRAS G12D inhibitors | 杭州英创医药科技有限公司 | 2025-01-24 | — | — | CN | disclosed |
| US-12152049-B2 | STING agonistic compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-11-26 | — | — | US | disclosed |
| CN-118638153-B | Preparation method of aminopyridine compound | 天津辰欣药物研究有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-112867725-B | Phosphate and phosphonate derivatives of 7-amino-5-thio-thiazolo [4,5-D ] pyrimidine modulators of CX3CR1 receptor and medical uses thereof | 坎塞拉有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118638153-A | Preparation method of aminopyridine compound | 天津辰欣药物研究有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-118325235-B | Flame-retardant antibacterial color master batch and preparation method thereof | 浙江三基色新材料有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-118480070-A | Preparation and application of spiro compound with blood pressure reducing effect | 山东如至生物医药科技有限公司 | 2024-08-13 | — | — | CN | disclosed |
| EP-3130593-A1 | PHENANTHROLINE PHOSPHONIC ACID DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Beryl Therapeutics, Inc. (CN) | 2017-02-15 | — | — | EP | disclosed |
| US-20170029452-A1 | PHENANTHROLINE PHOSPHONIC ACID DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | XIAMEN BERYL THERAPEUTICS, INC. (CN) | 2017-02-02 | — | — | US | disclosed |
| EP-2448950-B1 | SYNTHESIS OF N4-(2,2-DIMETHYL-4-[(DIHYDROGEN PHOSPHONOXY)METHYL]-3-OXO-5-PYRIDO[1,4]OXAZIN-6-YL)-5-FLUORO-N2-(3,4,5-TRIMETHOXYPHENYL)-2,4-PYRIMIDINEDIAMINE DISODIUM SALT | RIGEL PHARMACEUTICALS INC (US) | 2016-01-13 | — | — | EP | disclosed |
| US-20130274499-A1 | Synthesis of 2,4-Pyrimidinediamines | MIDCAP FINANCIAL TRUST | 2013-10-17 | — | — | US | disclosed |
| US-8481724-B2 | Synthesis of 2,4-pyrimidinediamines | RIGEL PHARMACEUTICALS, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-20130018185-A1 | Synthesis of 2,4-Pyrimidinediamines | RIGEL PHARMACEUTICALS, INC. (US) | 2013-01-17 | — | — | US | disclosed |
| US-8299242-B2 | Synthesis of 2,4-pyrimidinediamines | RIGEL PHARMACEUTICALS, INC. (US) | 2012-10-30 | — | — | US | disclosed |
| EP-2448950-A1 | SYNTHESIS OF N4- (2, 2-DIMETHYL-4- [ (DIHYDROGEN PHOSPHONOXY]-3-OXO-5-PYRIDO [1, 4]OXAZIN-6-YL)-5-FLUORO-N2- (3, 4, 5,-TRIMETHOXYPHENYL) -2, 4- PYRIMIDINEDIAMINE DISODIUM SALT | Rigel Pharmaceuticals, Inc. (US) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011002999-A1 | SYNTHESIS OF N4- (2, 2-DIMETHYL-4- [ (DIHYDROGEN PHOSPHONOXY ] -3-OXO-5-PYRIDO [1, 4] OXAZIN-6-YL)-5-FLUORO-N2- (3, 4, 5,-TRIMETHOXYPHENYL) -2, 4- PYRIMIDINEDIAMINE DISODIUM SALT | RIGEL PHARMACEUTICALS, INC. (US) | 2011-01-06 | — | — | WO | disclosed |
| US-20110003986-A1 | Synthesis of 2,4-Pyrimidinediamines | RIGEL PHARMACEUTICALS, INC. (US) | 2011-01-06 | — | — | US | disclosed |