⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28215763 | 0.81 | — | — | |
| SCHEMBL1463862 | 0.81 | — | — | |
| SCHEMBL18073206 | 0.80 | — | — | |
| SCHEMBL7565365 | 0.79 | — | — | |
| SCHEMBL18965994 | 0.79 | — | — | |
| SCHEMBL23482539 | 0.79 | MMP1 (0.36) | — | |
| SCHEMBL6902029 | 0.79 | ANPEP (0.34) | — | |
| SCHEMBL10451746 | 0.77 | MMP1 (0.48) | — | |
| SCHEMBL523330 | 0.75 | LTA4H (0.35) | — | |
| SCHEMBL523329 | 0.75 | LTA4H (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11793771-B2 | Immunomodulator compounds | CHEMOCENTRYX, INC. (US) | 2023-10-24 | — | — | US | disclosed |
| US-11759458-B2 | Indane-amines as PD-L1 antagonists | CHEMOCENTRYX, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| US-11708326-B2 | Immunomodulator compounds | CHEMOCENTRYX, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20180008554-A1 | IMMUNOMODULATOR COMPOUNDS | CHEMOCENTRYX, INC. | 2018-01-11 | — | — | US | disclosed |
| US-20070072934-A1 | Alkoxy indolinone based protein kinase inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-03-29 | — | — | US | disclosed |
| EP-0474955-B1 | Process for the preparation of N-phosphonomethylglycine by means of an oxidation/dealkylation process | MONSANTO CO (US) | 1995-07-19 | — | — | EP | disclosed |
| EP-0474955-A1 | Process for the preparation of N-phosphonomethylglycine by means of an oxidation/dealkylation process | MONSANTO COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-4965403-A | ALKALI METAL SALTS OF N-PHOSPHONOMETHYLGLYCINE | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0385014-A1 | Process for preparation of substituted aminomethylphosphonic acids | CROMPTON & KNOWLES CORPORATION (US) | 1990-09-05 | — | — | EP | disclosed |
| EP-0385010-A1 | N-alkyl-N-(Aminophenylsulfonyl)-aminoalkylphosphonic acids and salts | CROMPTON & KNOWLES CORPORATION (US) | 1990-09-05 | — | — | EP | disclosed |
| US-4851158-A | N-alkyl-N-(aminophenylsulfonyl)-aminoalkylphosphonic acids | CROMPTON & KNOWLES CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| US-4830788-A | Process for preparation of substituted-aminomethylphosphonic acids | CROMPTON & KNOWLES CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| US-4804500-A | Amine dealkylation process | MONSANTO COMPANY (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0199702-B1 | AMINE DEALKYLATION PROCESS | Monsanto Company (US) | 1988-12-21 | — | — | EP | disclosed |
| EP-0199702-A1 | Amine dealkylation process | Monsanto Company (US) | 1986-10-29 | — | — | EP | disclosed |
| EP-0186648-A1 | Process for the preparation of glyphosate and glyphosate derivatives | Monsanto Company (US) | 1986-07-02 | — | — | EP | disclosed |