Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | ACR | P10323 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304204 | 0.91 | MAPT (0.56) | MAPTALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL8912717 | 0.87 | MAPT (0.55) | MAPTALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL8912381 | 0.86 | MAPT (0.51) | MAPTALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL8913234 | 0.86 | MAPT (0.53) | MAPTALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL8915721 | 0.86 | MAPT (0.53) | MAPTALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL8962384 | 0.85 | MAPT (0.50) | MAPTALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL9196298 | 0.85 | KMT2A (0.61) | MAPTKMT2ALMNACYP1A2CYP2D6 | |
| SCHEMBL11769419 | 0.85 | LMNA (0.62) | MAPTALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL10656997 | 0.85 | LMNA (0.62) | MAPTALDH1A1KMT2ALMNACYP1A2 | |
| SCHEMBL9193553 | 0.83 | LMNA (0.70) | MAPTALDH1A1KMT2ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471277-B1 | Silanol compounds, polymerizable monomers and polymers having mesogenic groups | SAGAMI CHEM RES (JP) | 1995-11-15 | — | — | EP | disclosed |
| US-5329034-A | Silanol compounds, polymerizable monomers and polymers having mesogenic groups | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0471277-A2 | Silanol compounds, polymerizable monomers and polymers having mesogenic groups | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-02-19 | — | — | EP | disclosed |