Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9436760 | 0.99 | SLC9A1 (0.62) | SLC9A1ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL9196821 | 0.89 | SLC9A1 (0.67) | SLC9A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9436766 | 0.86 | SLC9A1 (0.68) | SLC9A1 | |
| SCHEMBL9436763 | 0.86 | MAPT (0.55) | ALDH1A1KDM4EMAPTALOX15HTT | |
| SCHEMBL9195350 | 0.85 | ALDH1A1 (0.49) | SLC9A1ALDH1A1KDM4EMAPTALOX15 | |
| Hydrochloric Acid SCHEMBL9197008 | 0.84 | ALDH1A1 (0.49) | SLC9A1ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL9192622 | 0.80 | SLC9A1 (0.73) | SLC9A1ERAP1 | |
| Hydrochloric Acid SCHEMBL9436682 | 0.79 | SLC9A1 (0.72) | SLC9A1ERAP1 | |
| SCHEMBL3906519 | 0.78 | SLC9A1 (1.00) | SLC9A1 | |
| SCHEMBL29357040 | 0.78 | SLC9A1 (1.00) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416499-B1 | Benzoylguanidines, process for their preparation, their use as medicaments as well as medicament containing them | HOECHST AG (DE) | 1995-04-26 | — | — | EP | disclosed |
| US-5292755-A | USPA benzolyguanidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| US-5091394-A | BENZOYLGUANIDINES, A PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| EP-0416499-A2 | Benzoylguanidines, process for their preparation, their use as medicaments as well as medicament containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-13 | — | — | EP | disclosed |