SCHEMBL9195368

SCHEMBL9195368

CCCN([C]=O)C(=O)OCC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
LMNA P02545 3/20 0.36
HSD17B10 Q99714 2/20 0.36
ALOX15 P16050 1/20 0.34
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
SOAT1 P35610 1/20 0.34
GLO1 Q04760 1/20 0.32
TRPA1 O75762 1/20 0.32
TSHR P16473 2/20 0.31
HPGD P15428 1/20 0.31
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP2C9 P11712 1/20 0.31
POLB P06746 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11519164 0.88 CA12 (0.35) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL11517386 0.85 DNM1 (0.38) ALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL11517198 0.85 DNM1 (0.38) ALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL11521795 0.85 DNM1 (0.38) ALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL11519833 0.85 DNM1 (0.38) ALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL5454379 0.83 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL5571588 0.81 ALDH1A1 (0.32) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL6408878 0.81 CA12 (0.32) HSD17B10TSHRCA12CA2CA9
SCHEMBL5567612 0.76 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL10087947 0.73 CA12 (0.46) ALDH1A1LMNAHSD17B10ALOX15MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032252-A1 THERAPEUTIC AGENT FOR HUMORAL IMMUNITY-RELATED DISEASES IN MATERNO-FETAL RELATIONSHIP 山口 晃史 2020-02-13 WO disclosed
CN-107106588-A Agent for improving pregnancy status and use thereof 山口晃史 2017-08-29 CN disclosed
CN-101501034-A 1, 7-naphthyridine derivatives as inhibitors of p38 mitogen-activated protein kinase ALMIRALL LAB (ES) 2009-08-05 CN disclosed
CN-1229111-C Sustained release preparations FUJISAWA PHARMACEUTICAL CO (JP) 2005-11-30 CN disclosed
CN-1149979-C Pharmaceutical composition ����ҩƷ��ҵ��ʽ���� 2004-05-19 CN disclosed
CN-1301157-A Sustained release preparations FUJISAWA PHARMACEUTICAL CO (JP) 2001-06-27 CN disclosed
CN-1259053-A Pharmaceutical composition FUJISAWA PHARMACEUTICAL CO (JP) 2000-07-05 CN disclosed
CN-1245424-A Medicinal composition FUJISAWA PHARMACEUTICAL CO (JP) 2000-02-23 CN disclosed
EP-0676961-A1 USE OF MACROLIDES FOR THE TREATMENT OF CEREBRAL ISCHEMIA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-10-18 EP disclosed
US-4139390-A Presensitized printing plate having a print-out image EASTMAN KODAK COMPANY (US) 1979-02-13 US disclosed