Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | CA7 | P43166 | 4/20 | 0.59 |
| ▸ | CA9 | Q16790 | 4/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775789 | 0.82 | CA12 (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27708056 | 0.76 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13401343 | 0.76 | LMNA (0.65) | TDP1ALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL7735421 | 0.75 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5788019 | 0.75 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24186432 | 0.74 | CA12 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14452075 | 0.74 | ALDH1A1 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27906900 | 0.74 | ALDH1A1 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27906903 | 0.74 | ALDH1A1 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14106874 | 0.74 | ALDH1A1 (0.65) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321846-B1 | Pyrimidine derivatives, processes for their production, and herbicidal method and compositions | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-5081244-A | PYRIMIDINE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION, AND HERBICIDAL METHOD AND COMPOSITIONS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| US-4906285-A | Pyrimidine derivatives and herbicidal method and compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0321846-A2 | Pyrimidine derivatives, processes for their production, and herbicidal method and compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-06-28 | — | — | EP | disclosed |