Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8793050 | 0.85 | MAPT (0.52) | MAPTHPGDHTTNPSR1ALDH1A1 | |
| SCHEMBL8794975 | 0.83 | KMT2A (0.58) | MAPTHPGDHTTNPSR1ALDH1A1 | |
| SCHEMBL8793898 | 0.82 | RAB9A (0.52) | MAPTHPGDHTTNPSR1ALDH1A1 | |
| SCHEMBL7333685 | 0.80 | KMT2A (0.65) | MAPTHPGDHTTNPSR1ALDH1A1 | |
| SCHEMBL26544897 | 0.79 | KMT2A (0.61) | MAPTHPGDHTTNPSR1ALDH1A1 | |
| SCHEMBL13059438 | 0.77 | KMT2A (0.68) | MAPTHPGDHTTNPSR1ALDH1A1 | |
| SCHEMBL28263863 | 0.76 | KMT2A (0.63) | MAPTHPGDHTTNPSR1ALDH1A1 | |
| SCHEMBL8795974 | 0.75 | KMT2A (0.54) | MAPTHPGDHTTNPSR1ALDH1A1 | |
| SCHEMBL14996180 | 0.74 | KMT2A (0.67) | MAPTNPSR1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL7650881 | 0.73 | KMT2A (0.60) | MAPTHPGDHTTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634401-A1 | MDR reversal agents | AMERICAN CYANAMID COMPANY (US) | 1995-01-18 | — | — | EP | disclosed |