Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195868 | 1.00 | CHRM2 (0.31) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL30752652 | 0.82 | PPM1D (0.32) | — | |
| SCHEMBL35210460 | 0.82 | PPM1D (0.32) | — | |
| SCHEMBL9190586 | 0.81 | CHRM2 (0.56) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9190583 | 0.81 | CHRM2 (0.56) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL28529851 | 0.79 | PLA2G7 (0.30) | — | |
| SCHEMBL21389421 | 0.79 | BRD4 (0.33) | — | |
| SCHEMBL21389115 | 0.79 | PLA2G7 (0.30) | — | |
| SCHEMBL28537661 | 0.79 | BRD4 (0.33) | — | |
| SCHEMBL28536009 | 0.79 | PLA2G7 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381984-B1 | 3- or 4-substituted oxotremorine derivatives | AMERICAN CYANAMID CO (US) | 1995-04-19 | — | — | EP | disclosed |
| US-5089518-A | 3- or 4-substituted oxotremorine derivatives and a method of treating cholinergic dysfunction therewith | AMERICAN CYANAMID COMPANY (US) | 1992-02-18 | — | — | US | disclosed |
| US-4952600-A | TREATING DISORDERS OF THE CENTRAL NERVOUS SYSTEM | AMERICAN CYANAMID COMPANY (US) | 1990-08-28 | — | — | US | disclosed |
| EP-0381984-A1 | 3- or 4-substituted oxotremorine derivatives | AMERICAN CYANAMID COMPANY (US) | 1990-08-16 | — | — | EP | disclosed |
| US-4937235-A | Anticholinergic agents | AMERICAN CYANAMID COMPANY (US) | 1990-06-26 | — | — | US | disclosed |