Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198250 | 0.88 | CYP1A2 (0.45) | ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9 | |
| SCHEMBL9156889 | 0.84 | CYP1A2 (0.42) | ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9 | |
| SCHEMBL8801724 | 0.81 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9 | |
| SCHEMBL9190641 | 0.80 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9 | |
| SCHEMBL9197640 | 0.79 | CYP1A2 (0.47) | ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9 | |
| SCHEMBL9195996 | 0.79 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9 | |
| SCHEMBL8659409 | 0.79 | NPSR1 (0.39) | ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9 | |
| SCHEMBL27377682 | 0.78 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9 | |
| SCHEMBL28054700 | 0.77 | CYP1A2 (0.46) | ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9 | |
| SCHEMBL9730567 | 0.76 | CYP1A2 (0.45) | ALDH1A1SMN1; SMN2NPSR1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321846-B1 | Pyrimidine derivatives, processes for their production, and herbicidal method and compositions | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-5081244-A | PYRIMIDINE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION, AND HERBICIDAL METHOD AND COMPOSITIONS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| US-4906285-A | Pyrimidine derivatives and herbicidal method and compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0321846-A2 | Pyrimidine derivatives, processes for their production, and herbicidal method and compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-06-28 | — | — | EP | disclosed |