Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547413 | 0.80 | MEN1 (0.44) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL9197459 | 0.80 | ECE1 (0.42) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL9197796 | 0.74 | TOP2B (0.46) | MEN1KMT2APOLBBLMNSD2 | |
| Hydrochloric Acid SCHEMBL9200372 | 0.72 | TOP2B (0.46) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL9195854 | 0.72 | ECE1 (0.53) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL9200709 | 0.71 | TERT (0.49) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL9511619 | 0.71 | CA12 (0.51) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL9197269 | 0.71 | ECE1 (0.48) | MEN1KMT2APOLBBLMNSD2 | |
| SCHEMBL9195999 | 0.71 | MEN1 (0.49) | MEN1KMT2APOLBBLMNSD2 | |
| Hydrochloric Acid SCHEMBL9271897 | 0.70 | ECE1 (0.52) | MEN1KMT2APOLBBLMNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574433-B1 | 6,9-BIS(AMINO SUBSTITUTED)BENZO g]PHTHALAZINE-5,10-DIONES AS ANTITUMOR AGENTS | BOEHRINGER MANNHEIM ITALIA (IT) | 1995-05-31 | — | — | EP | disclosed |